FROM A REVIEW BY THE GUARDIAN
“When Johann Hari was 18 he took his first antidepressant. That morning he had visited a doctor and explained how, ever since he was small, he had battled with feelings of overwhelming sadness. When he wasn’t taking himself off to cry quietly, an anxious monologue would be running in his head. “Get over it,” it would say, “stop being so weak.” The doctor was reassuring, explaining that these feelings were to be expected since Hari was one of many people whose brain had depleted levels of serotonin. And so he prescribed some pills that would restore the balance. As Hari swallowed his first tablet, he says, “it felt like a chemical kiss”.
It wasn’t until he was in his 30s that he thought of all the questions the doctor didn’t ask, such as: what was his life like? What was making him sad? What changes could be made to make life more tolerable? The push and pull between “reactive” depression (the kind that relates to our environment and life experience) and “endogenous” depression (where something goes wrong in the brain) forms the basis of Lost Connections, an eye-opening, highly detailed though sometimes frustrating investigation into the causes and cures of depression.”